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PygeumPrunus africana bark extract

Moderate evidenceReviewed September 19, 2026

African cherry bark extract with a long history in European urology and a Cochrane review that found modest symptom improvement. Frequently named in forum threads about nighttime urination.

Dose used in trials
100 to 200 mg/day of standardized bark extract
Time to effect
6 to 8 weeks

What the evidence says

A Cochrane review of 18 trials (1,562 men) found men taking pygeum were about twice as likely to report symptom improvement, with fewer nighttime trips and better flow. The trials were short, small and mostly old, and none reported prostate volume.

What it is

Bark extract from Prunus africana, used in France and Germany as a prescription-grade phytotherapy for decades. It contains phytosterols and ferulic acid esters thought to reduce prostate inflammation and swelling.

What the trials found

Nighttime urination fell by about 19 percent and peak flow rose by about 23 percent in the pooled Cochrane data. Those are real but modest numbers, in trials of a few weeks to a few months.

It is one of the supplements Reddit users most often credit with fewer nighttime trips. Anecdote, again, but consistent with the trials.

Side effects

  • Mild stomach upset in a small minority
  • Otherwise a placebo-like safety profile in trials

Interactions

  • None documented; no reports with tamsulosin or finasteride
Our pick on Amazon

NOW Pygeum and Saw Palmetto with pumpkin seed oil, 120 softgels

Choose a standardized extract with a milligram figure. Wild-harvested pygeum is a conservation concern, so prefer brands that state cultivated sourcing.

Check price on Amazon

As an Amazon Associate we earn from qualifying purchases. Buy from the brand or an authorised seller; forum users report counterfeit supplements from third-party sellers.

Frequently asked questions

Pygeum or saw palmetto?
Pygeum's trial record is more consistently positive; saw palmetto's is larger but split. Neither shrinks the prostate.

Other prostate ingredients

This article is for information only and is not medical advice. Statements about supplements have not been evaluated by the FDA. Do not start, stop or combine supplements with prescription medication without talking to your doctor or pharmacist. If you cannot pass urine, or have chest pain, confusion or fainting, seek emergency care.

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